2. Signaling Pathways
  3. Stem Cell/Wnt
  4. Hippo (MST)
  5. MST2 Isoform
  6. MST2 Activator

MST2 Activator

MST2 Activator (1):

Cat. No. Product Name Effect Purity
  • HY-186148
    YL-602
    		Activator
    YL-602 is an orally active Hippo pathway activator. YL-602 activates the Hippo pathway via MST1/2, with downstream pathway activation. YL-602 inhibits YAP and CTGF expression in cells irrespective of cell density and serum presence. YL-602 induces tumor cell apoptosis and inhibits colony formation. YL-602 suppresses tumor growth in mice. YL-602 can be used for the research of cancer, such as breast cancer.